Photo by Carolzinha

Find Luxury Hotels in San Isidro

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Top Luxury Hotels in San Isidro

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to San Isidro?
Use Expedia to arrange your flight to Buenos Aires (AEP-Aeroparque Jorge Newbery) airport or Buenos Aires (EZE-Ministro Pistarini Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you’d like to make your stay special. If you want a posh hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that San Isidro offers. San Isidro has some interesting things to see and do including San Isidro Hippodrome and San Isidro Cathedral, so you might want to take in the local sights during your visit.
What's the best luxury hotel in San Isidro?
Hotel del Casco is a 4-star hotel with spa services and a terrace, and it’s a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in San Isidro?
Planning for the weather is a good way to make your trip to San Isidro relaxing and enjoyable, especially when you’re splurging. The hottest months are usually January and February, with an average temperature of 24°C, while the coldest months are July and June, with an average of 12°C. Average annual precipitation for San Isidro is 1142 mm.
What's there to see and do in San Isidro?
Experience San Isidro with a stop at San Isidro Hippodrome, San Isidro Cathedral and Plaza Mitre. If you have extra time while you’re in the area, you might want to stop by Palermo Soho and Obelisco.
How can I get around San Isidro?
It’s easier to get around town comfortably when you know your options. Metro stations nearby include San Isidro C Station and San Isidro R Station.