O Brien Hotels from S$84

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 trending O Brien hotels

Hampton Inn & Suites Alachua I-75

2.5 star property
9.4 out of 10, Exceptional, (430)
"Dog friendly "
The price is S$161
includes taxes & fees
3 Aug - 4 Aug
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

2.0 star property
4.8 out of 10, (569)
"clean, check in easy"
The price is S$91
includes taxes & fees
22 Jul - 23 Jul
Americas Best Value Inn Alachua

Royal Inn

2.0 star property
7.2 out of 10, Good, (178)
"Not top of the line but a nice budget hotel"
The price is S$94
includes taxes & fees
23 Jul - 24 Jul
Royal Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.4 out of 10, Exceptional, (1003)
"Really enjoyed our stay! "
The price is S$150
includes taxes & fees
24 Jul - 25 Jul
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Vista Verde Farm Retreat

2.0 star property
9.8 out of 10, Exceptional, (6)
"This is my second time staying on this property and I love it "
The price is S$244
includes taxes & fees
23 Jul - 24 Jul
Vista Verde Farm Retreat

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (360)
"Amazing owners"
The price is S$155
includes taxes & fees
22 Jul - 23 Jul
BlueGem Motel

High Springs Country Inn

2.0 star property
7.6 out of 10, Good, (4)
"The facility met all expectations as a basic, older, roadside motel in a small, rural town, run by a family who lives next to property. It was clean, but furniture and interior spaces are dated and worn. It served the purpose of an overnight stay prior to a kayak trip the next day. Staff was friendly, ice machine worked, water was hot NOT fancy, but served the purpose, given the reasonable price point. "
The price is S$105
includes taxes & fees
24 Jul - 25 Jul
High Springs Country Inn

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (549)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is S$97
includes taxes & fees
22 Jul - 23 Jul
Palms Garden Inn

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (141)
"Beautiful hotel! Elegant, classy. Loved it! "
The Blanche

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1002)
"It s a very nice hotel"
The price is S$92
includes taxes & fees
22 Jul - 23 Jul
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (53)
"the cabin was amazing, great amenities i would recommend!!"
The price is S$204
includes taxes & fees
23 Jul - 24 Jul
Postcard Cabins Gilchrist Springs

Super 8 by Wyndham Lake City

2.0 star property
7.2 out of 10, Good, (628)
"Good breakfast nice pool and a great price "
The price is S$97
includes taxes & fees
23 Jul - 24 Jul
Super 8 by Wyndham Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (736)
"Sufficient for a nights stay. A bit outdated, but for the price that’s kind of expected. "
The price is S$94
includes taxes & fees
25 Jul - 26 Jul
Driftwood Inn

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (516)
"Great staff great stay"
The price is S$95
includes taxes & fees
22 Jul - 23 Jul
Regal Inn

Courtyard By Marriott Lake City

3.0 star property
9.6 out of 10, Exceptional, (114)
"Hotel staff was very friendly. Hotel was very clean and super fancy. "
The price is S$152
includes taxes & fees
27 Jul - 28 Jul
Courtyard By Marriott Lake City

Days Inn by Wyndham Lake City I-75

2.0 star property
7.4 out of 10, Good, (1009)
"Close to interstate, clean, friendly staff"
The price is S$97
includes taxes & fees
23 Jul - 24 Jul
Days Inn by Wyndham Lake City I-75

Knights Inn Lake City

1.5 star property
5.4 out of 10, (626)
"Love this place!!"
The price is S$87
includes taxes & fees
22 Jul - 23 Jul
Knights Inn Lake City

Holiday Inn & Suites Lake City by IHG

3.0 star property
8.6 out of 10, Excellent, (1007)
"Out dated but comfortable. Close to restaurant s."
The price is S$126
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

2.5 star property
7.8 out of 10, Good, (908)
"Great value for the money. Close to a lot of restaurants."
The price is S$101
includes taxes & fees
23 Jul - 24 Jul
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1002)
"Clean modern hotel and served our purpose."
The price is S$142
includes taxes & fees
22 Jul - 23 Jul
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

Photo by Dr__Vlad
Open Photo by Dr__Vlad

Top O Brien Hotel Reviews

Frequently asked questions

Where is the best place to stay in O Brien?

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

What's the best hotel for a romantic holiday to O Brien?

Your Safari on the Suwannee River is a favourite property for couples, and features in-room kitchens and private patios.

What's the best pet-friendly place to stay in O Brien?

Your Safari on the Suwannee River is a top property for people travelling with their pets and offers in-room kitchens for its human guests.

What are some accommodation options with pools in O Brien?

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.

How is it to stay in O Brien?

Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodation options to choose from. Find out more about O Brien.

What are the top places to visit in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.

What's the seasonal weather in O Brien?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.