
Medical Center District Holidays
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Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District

Downtown San Antonio
5 out of top 10 points of interest in this area
4.5/5(42 area reviews)
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.
Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is S$135 per night from 20 Jul to 21 Jul
S$135
20 Jul - 21 Jul
includes taxes & fees
8.4/10 Very Good! (2,731 reviews)
"Great location for my purpose of being there. Employees all helpful and nice."
Reviewed on 16 Jul, 2025

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is S$133 per night from 31 Jul to 1 Aug
S$133
31 Jul - 1 Aug
includes taxes & fees
8.4/10 Very Good! (1,025 reviews)
"standard hotel but on top of service"
Reviewed on 14 Jul, 2025

Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is S$152 per night from 27 Jul to 28 Jul
S$152
27 Jul - 28 Jul
includes taxes & fees
9.2/10 Wonderful! (1,284 reviews)
Great friendly service! Hotel needs more upkeep!
"We’ve stayed here several times but this time it was more run down than usual. Only 1/3 elevators was working, carpets seemed dirtier than normal and on our first night swimming there was poop by the stairwell. I will say the staff is amazing and friendly."
Reviewed on 13 Jul, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns
S$46
per adult
92% of travellers recommend