Mayo Clinic Holidays

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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most. Learn more about Mayo Clinic
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Known for its ample dining options and great live music, there's plenty to explore in Downtown Phoenix. You can visit top attractions like Chase Field and Footprint Center, and jump on the metro at 12th Street - Jefferson Station or 12th Street - Washington Station to see more of the city.

Find hotels in Downtown Phoenix

Top hotels in Mayo Clinic

Wyndham Phoenix Airport/Tempe
Wyndham Phoenix Airport/Tempe
3.5 out of 5
1600 S 52nd St, Tempe, AZ
Fully refundableReserve now, pay when you stay
The price is S$123 per night from 25 Dec to 26 Dec
S$123
includes taxes & fees
25 Dec - 26 Dec
7.6/10 Good! (1,498 reviews)
"Nice renovations complete new carpet, newly renovated rooms, working on the weight room. Beautiful pool and balconys overlooking the pool and hot tub area. Beautiful large fireplace in the pool area. Only issue, the floor was not clean, and add to request toilet paper, shower gel, coffee, and towels, ..."

Reviewed on 26 Nov,2024

Wyndham Phoenix Airport/Tempe
FOUNDRE Phoenix
FOUNDRE Phoenix
4 out of 5
1100 N Central Avenue, Phoenix, AZ
Fully refundableReserve now, pay when you stay
The price is S$282 per night from 26 Dec to 27 Dec
S$282
includes taxes & fees
26 Dec - 27 Dec
9/10 Wonderful! (1,428 reviews)
"The staff were amazing! Having an art gallery to peruse at your leisure was delightful."

Reviewed on 28 Nov,2024

FOUNDRE Phoenix
The Scottsdale Plaza Resort & Villas
The Scottsdale Plaza Resort & Villas
4 out of 5
7200 N Scottsdale Rd, Paradise Valley, AZ
Fully refundableReserve now, pay when you stay
The price is S$286 per night from 2 Dec to 3 Dec
S$286
includes taxes & fees
2 Dec - 3 Dec
8.8/10 Excellent! (2,090 reviews)
"Great spot"

Reviewed on 26 Nov,2024

The Scottsdale Plaza Resort & Villas
See all 13,255 properties in Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mayo Clinic holiday package cost?
Starting from as low as , a package is your gateway to low-priced travel. Customize your Mayo Clinic trip by choosing from our extensive range of hotels, flights and rental cars.
How do I get a cheap travel package to Mayo Clinic?
Our Mayo Clinic holiday packages promise plenty of savings for the savvy globetrotter. For the best deals, simply combine your flights, hotels and activities into an affordable package. But low prices are just the beginning of your next unforgettable adventure. Book with Expedia and and you’ll have over 550 airlines and 1,000,000 properties throughout the world to pick from. No matter your budget or style, there’s a holiday package that’s perfect for you.
Where should I stay in Mayo Clinic?
Cross Tournament Players Club of Scottsdale off your must-see list and then stay right near it. Soak up the exciting vibe around this terrific attraction and drop by whenever the mood strikes!
What are the top hotels in Mayo Clinic?
Whether you plan to stay for a night or a week in Mayo Clinic, you’ll get a great night’s rest at Sonesta Select Scottsdale at Mayo Clinic Campus. This option is popular with plenty of travellers.
How far in advance should I book my Mayo Clinic holiday?
Search Expedia to compare international flights as early as possible. In most cases, you can purchase a seat up to 12 months prior to departure. If it’s too early for your preferred carrier, or you have to book last minute, don’t despair. Cheap fares to Mayo Clinic sometimes occur within weeks of departure.
What does an Expedia Mayo Clinic travel package include?
It all depends on what sort of trip you have in the works. Mayo Clinic holiday deals can include car rentals, hotels and flights. You can mix and match to find the travel package that suits your style and budget. You can also add on activities and experiences after you’ve booked to score even bigger discounts.
What should I know before booking a Mayo Clinic travel package?
When you book your flights, hotels and car rentals together, you’ll walk away with awesome discounts. Whether you’re planning a beach break in a villa or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Mayo Clinic Expedia holiday package?
You can, and with over 550 airlines to choose from all over the world, you’ve got lots of choice. Take a look at the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mayo Clinic holiday package?
You sure can, and we’ll help you every step of the way. You may be able to cancel and rebook your Mayo Clinic holiday package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, have a look at our Customer Service Portal for further information.

Popular places to visit

Phoenix Convention Center

Phoenix Convention Center

3.5/5(2 reviews)

During your trip, find out what's happening in Phoenix Convention Center, a top convention centre in Phoenix. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Phoenix Convention Center
Westgate Entertainment District

Westgate Entertainment District

4/5(3 reviews)

You can browse for the perfect souvenirs at Westgate Entertainment District during your stay in Glendale. Experience the area's great live music or attend a sporting event.

Westgate Entertainment District
Phoenix Zoo featuring zoo animals

Phoenix Zoo

5/5(3 reviews)

One of the best destinations in the United States for families is home to some of its most interesting animals.

Phoenix Zoo

Things to do

Hot Air Balloon Ride in Phoenix

Morning Hot Air Balloon Ride Over Phoenix

S$318
Per adult
98% of travellers recommend
Morning Hot Air Balloon Ride Over Phoenix
Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

S$181
Per adult
100% of travellers recommend
Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert
Picture 2 for Activity Phoenix: Ghosts & Poltergeists Guided Haunted Walking Tour

Phoenix: Ghosts & Poltergeists Guided Haunted Walking Tour

S$34
Per adult
Phoenix: Ghosts & Poltergeists Guided Haunted Walking Tour
See all activities in Phoenix

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.