Lake Nona Medical City Holidays

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    Better together

    Save up to S$134 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place
Price found within the past 48 hours. Click for updated prices.
Palazzo Lakeside Hotel

Palazzo Lakeside Hotel

3 out of 5
Save 100% on your flight
per person
7 Sept - 14 Sept
found 18 hours ago
Return flight included
New York (NYC) to Orlando (MCO)
8.2/10 Very Good! (5,121 reviews)
Great staff and breakfast

Reviewed on 14 Jul, 2025

Westgate Town Center Resort

Westgate Town Center Resort

4 out of 5
Save 100% on your flight
per person
7 Sept - 14 Sept
found 18 hours ago
Return flight included
New York (NYC) to Orlando (MCO)
8/10 Very Good! (1,277 reviews)
The outlooks of the property is good however the facilities are too old. No room cleaning services makes me so upsets.

Reviewed on 14 Jul, 2025

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area

4 out of 5
Save 100% on your flight
per person
7 Sept - 14 Sept
found 18 hours ago
Return flight included
New York (JFK) to Orlando (MCO)
8.2/10 Very Good! (5,060 reviews)
The property was good and nice but the water park in some areas were way too expensive

Reviewed on 15 Jul, 2025

Seasons Florida Resort

Seasons Florida Resort

2 out of 5
Save 100% on your flight
per person
7 Sept - 14 Sept
found 18 hours ago
Return flight included
New York (JFK) to Orlando (MCO)
8.8/10 Excellent! (2,970 reviews)
The staff was very accommodating and everything was very clean

Reviewed on 14 Jul, 2025

The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Save 100% on your flight
per person
7 Sept - 14 Sept
found 18 hours ago
Return flight included
New York (JFK) to Orlando (MCO)
9.6/10 Exceptional! (1,000 reviews)
Clean, quiet, professional staff and cute area. Just my style. Will definitely stay here again!

Reviewed on 14 Jul, 2025

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
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International Drive District

1 out of top 10 points of interest in this area

Visitors to International Drive District rave about its breathtaking beach views, exciting theme parks and popular shops. You might also want to make some time to see Aquatica or The Orlando Eye at ICON Park while you're exploring the neighbourhood.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

Hyatt Regency Orlando International Airport
Hyatt Regency Orlando International Airport
4 out of 5
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is S$244 per night from 16 Jul to 17 Jul
S$244
16 Jul - 17 Jul
includes taxes & fees
9.4/10 Exceptional! (3,377 reviews)
"Clean"

Reviewed on 12 Jul, 2025

Hyatt Regency Orlando International Airport
DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando
4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is S$121 per night from 4 Aug to 5 Aug
S$121
4 Aug - 5 Aug
includes taxes & fees
8.2/10 Very Good! (6,446 reviews)
"Great experience, returning couple times"

Reviewed on 12 Jul, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Marriott's Grande Vista
Marriott's Grande Vista
4 out of 5
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is S$137 per night from 4 Aug to 5 Aug
S$137
4 Aug - 5 Aug
includes taxes & fees
8.8/10 Excellent! (2,615 reviews)
"This property had everything we needed to have a great relaxing weekend. I am looking forward to returning as soon as I can."

Reviewed on 12 Jul, 2025

Marriott's Grande Vista
See all 27,292 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Lake Nona Medical City holiday package cost?
The cheapest Lake Nona Medical City package is S$347, so your dream trip can become a reality --- without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City holiday package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes travelling cheap and easy. And with more than 550 air carriers and 1,000,000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Centre at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City holiday?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organise your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including holiday rentals like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia holiday package?
Yes --- and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City holiday package?
Don't worry if you're rethinking your Lake Nona Medical City holiday package --- you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Popular places to visit

VA Medical Center at Lake Nona

If VA Medical Center at Lake Nona is what brings you to town, hopefully you'll have a chance to explore more of Orlando.

VA Medical Center at Lake Nona

University of Central Florida College of Medicine

Enjoy the student vibe at University of Central Florida College of Medicine during your stay in Orlando. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.

University of Central Florida College of Medicine

Things to do

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Aquatica Orlando

S$69
per traveller
82% of travellers recommend
Aquatica Orlando
Explore the Wonderful World of the Oz Books in a way that you have never seen before...

Wizard of OZ Museum tour

S$38
per adult
100% of travellers recommend
Wizard of OZ Museum tour
Bamboo Dune Buggy Tour

Fort Meade: Bamboo Dune Buggy Tour

S$90
per adult
100% of travellers recommend
Fort Meade: Bamboo Dune Buggy Tour
See all activities in Orlando

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.