Find Cayo Guillermo Beach Resorts

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Top Beach Resorts in Cayo Guillermo

Hotel Grand Muthu Cayo Guillermo
Outdoor pool

Hotel Grand Muthu Cayo Guillermo

3.5 star property
Hotel Grand Muthu Cayo Guillermo
Iberostar Daiquirí - All inclusive
2 outdoor pools, pool umbrellas

Iberostar Daiquirí - All inclusive

4.0 star property
6.6 out of 10, (41)
"The location of the hotel, staff, food and entertainment are great. We felt it’s a well designed hotel (Believe just over 300 rooms) as it never felt overcrowded nor overlooked. The staff are wonderfully helpful and friendly and plenty around. "
Iberostar Daiquirí - All inclusive
Villa Gregorio
On the beach

Villa Gregorio

2.5 star property
7.6 out of 10, Good, (9)
"Zimmer ohne Fenster, schlechte ölige Pommes, unfreundliches Personal"
Villa Gregorio
Club Cayo Guillermo - All Inclusive
View from room

Club Cayo Guillermo - All Inclusive

3.5 star property
6.0 out of 10, (1)
"В целом неплохо. Отель вроде хороший но номера грязные и убитые. Кормят нормально. На пляже водоросли "
Club Cayo Guillermo - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Cayo Guillermo
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

What is Cayo Guillermo like for travellers who love the beach?
Discover your ideal place to stay in Cayo Guillermo, which has a lot to offer the traveller looking for a beach getaway.
What's the best accommodation option to stay near the beach in Cayo Guillermo?
Villa Gregorio is a top beachfront hotel with free breakfast and free parking, and it’s located close to Cayo Guillermo Beach . Other good options for your stay near the beach include Iberostar Daiquirí - All inclusive and Club Cayo Guillermo - All Inclusive.
How many beach hotels should I expect to find in Cayo Guillermo?
Expedia has 8 beach hotels in Cayo Guillermo that are great for your beachside getaway.
When's the best time for a beach holiday in Cayo Guillermo?
Plan your trip to the beach with a look at the seasons in Cayo Guillermo: The hottest months are usually August and September, with an average temperature of 28°C, while the coldest months are January and March, with an average of 24°C. Average annual precipitation for Cayo Guillermo is 1143 mm.
What is there to see and do around Cayo Guillermo?
After arriving and settling in at your accommodation of choice, you might want to venture out and explore. Discover a variety of local attractions, which include Cayo Guillermo Beach and Parque Natural el Bagá.