Santa Mesa Car Rental

Search and Compare from Car Companies in Santa Mesa

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

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Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What happens if I need to cancel my Santa Mesa car reservation?
Don’t stress! If you’re able to cancel your prepaid reservation at least six hours ahead of collecting the car, you’ll most likely receive a full refund. You’ll want to scan your rental policy as there are some exclusions. Jump onto our Customer Service Portal if you still have queries.
What types of cars can I rent in Santa Mesa?
Many visitors opt for economy cars in Santa Mesa. Motorists love them because of their affordability. Plus, their small size makes them perfect for cities, where streets are crowded and parking can be tough. But economy isn’t your only option. SUVs, full-size cars and compacts are up for grabs too. Whether you’re sticking around Santa Mesa or journeying beyond, we’ll have the wheels for you.
Why should I rent a Santa Mesa car with Expedia?
Expedia is your one-stop shop for all your vacation needs, including rental cars. With suppliers to pick from in Santa Mesa, we work hard to find you the lowest price possible. Whether you want to book a car, flights or a hotel, you’ll find exclusive offers and member prices on Expedia. Combine all your bookings into a vacation package for even bigger savings on your trip to Santa Mesa.
How do I find the best car rental deals in Santa Mesa with Expedia?
Whatever class of wheels you’re searching for, Expedia will help you track down the best deal. Simply compare offers from reliable rental suppliers and select the option that works for you. Want to drive away with even more in your wallet? Bundle your Santa Mesa car rental with hotel or flight bookings.
What do you need to rent a car in Santa Mesa?
Most rental companies will require two things — a valid driver’s license and a credit card in your name. If you’d like to opt out of the provider’s insurance plan, proof of your own coverage may also be needed. Check your policy so you know what to bring when it’s time to pick up your ride.
Can I drive in Santa Mesa with my U.S. Driver's license?
Yes. If you have a current U.S. License, you can drive in Santa Mesa. You’re not likely to need an International Driving Permit. Having said that, they are quite easy to pick up, so it could be a good idea to organize one anyway.
Can I rent a car for a month or longer in Santa Mesa?
Yes, which means you won’t have to rebook a rental vehicle in the middle of your vacation. Check out our long-term car rental deals page, enter your trip information and book a set of wheels to call your own for however long you want.
Where can I find a Santa Mesa car rental if I am younger than 25?
You’ll need to investigate the age policy of the Santa Mesa rental suppliers you’re interested in. If you’re under 25 years of age, some will charge additional costs. It’s good to know about this before arriving at the desk so you can have the funds ready. Each rental car company has its own terms and conditions for young drivers, so it pays to do your research.