Santa Isabel Car Rental

Search and Compare from Car Companies in Santa Isabel

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Frequently asked questions

What happens if I need to cancel my Santa Isabel car reservation?
Canceling your rental car six hours before the scheduled pickup time should allow for a complete refund. However, this is not always a given. It’s a good idea to check your itinerary and rental agreement. Still stuck for answers? Jump onto our Customer Service Portal.
Why should I rent a Santa Isabel car with Expedia?
With car rental companies to pick from in Santa Isabel, Expedia will help you find the perfect set of wheels. And when you combine your rental vehicle, flights and hotel into a package, you can save more on your entire Santa Isabel vacation. From affordable economy models to full-size sedans and more, Expedia will put you in the driver’s seat of your next memorable adventure.
How do I find the best car rental deals in Santa Isabel with Expedia?
Scoring the best deal on your Santa Isabel rental car is easy with Expedia. Choose your preferred ride, add some details and compare prices across major brands. Why not add flights and hotels to your booking? You’ll score even bigger savings when you combine your bookings into a package.
What do you need to rent a car in Santa Isabel?
Two things — your driver’s license and a credit card in the same name. Car rental companies will offer you insurance, which is optional. But you may be asked to provide proof of alternative coverage if you opt out. Check with your supplier to avoid any hassles.
Can I drive in Santa Isabel with my U.S. Driver's license?
Yes, just make sure your license is current. But consider getting an International Driving Permit anyway. They’re relatively easy to organize, and with one, you’re licensed to drive in other places if your vacation plans extend beyond Santa Isabel.
Can I rent a car for a month or longer in Santa Isabel?
Yes, which means you won’t need to rebook a rental car mid-vacation. Go to our long-term car rental deals page, enter your trip details and lock in a ride that’s all yours for the length of your escape.
Where can I find a Santa Isabel car rental if I am younger than 25?
Age policies are different between rental suppliers, so you’ll have to do a bit of shopping around. Managed to find a Santa Isabel supplier that does rent to drivers under the age of 25? Awesome! Just be aware that an extra charge often applies to drivers aged between 21 and 24. The fine print of each rental car you’re looking at will have all the information you need.