Panama Car Rental

Search and Compare from Car Companies in Panama

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What happens if I need to cancel my Panama car reservation?
If you need to change your plans, almost all rentals qualify for a total refund. You’ll just need to let us know a minimum of six hours in advance of the arranged pickup time. Read through your cancellation policy for any exceptions. Your booking details will have more details, or you can visit our Customer Service Portal for more information.
Why should I rent a Panama car with Expedia?
Score an amazing deal on your wheels with Expedia. Economy or full-size, you’ll find your dream ride from one of the suppliers in Panama. Our special offers, rewards programs and member prices will help you get the most out of your travel budget. And if you’d like to save even more, combine your bookings into a vacation package. Add a flight or hotel to your rental car reservation and get access to awesome discounts!
How do I find the best car rental deals in Panama with Expedia?
Browse our extensive range of car rentals, check out customer ratings and compare offers from popular suppliers. In a few easy clicks, Expedia will help you score the best deal on your ride. Got a flight or hotel booking? Add on your Panama car rental to save even more money.
What do you need to rent a car in Panama?
Most rental companies will ask for these two things — your driver’s license and credit card. If you want to opt out of the supplier’s insurance plan, proof of other coverage may also be needed. Read your policy so you know what to bring when it’s time to collect your car.
Can I rent a car for a month or longer in Panama?
You can. Expedia partners with reputable companies that offer weekly and monthly rentals for many car classes. Snap up one of our long-term car rental deals and discover every part of Panama — or way beyond!
Where can I find a Panama car rental if I am younger than 25?
If you’re a younger driver hoping to rent a vehicle in Panama, it’d be wise to check the terms and conditions of the various rental companies you’re interested in. Some may rent to drivers under the age of 25, some may not. There may be extra costs if you’re between 21 and 24 years old. To avoid any surprise fees and charges at the rental counter, make sure you know if any extra charges apply to you.