Mayo Clinic Car Rental

Search and Compare from Car Companies in Mayo Clinic

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What happens if I need to cancel my Mayo Clinic car reservation?
When you cancel at least six hours prior to the pickup time, most prepaid bookings offer a total refund. However, not every one is eligible for this, so it’s important to read the cancellation policy. Read through your itinerary for the details or visit our Customer Service Portal to find out more.
Why should I rent a Mayo Clinic car with Expedia?
From our member exclusive offers and discounts to our handy vacation packages, there are so many reasons to rent your next car with Expedia. On your way to Mayo Clinic? There are car rental companies to select from, with plenty of vehicles to suit every style and budget. If you’d like to save more, bundle your car rental with your flights and hotel. Ready to take the wheel? We’re ready to get you on your way.
How do I find the best car rental deals in Mayo Clinic with Expedia?
Check out customer ratings and reviews, choose your favorite ride and compare prices from leading brands. Expedia makes it a cinch to track down the best deal on your rental wheels. Bundle your Mayo Clinic car rental with hotel or flight bookings and start your road trip with even more savings.
What do you need to rent a car in Mayo Clinic?
Any rental company you select will ask for these two things — a current driver’s license and a credit card in your name. If you’d prefer to opt out of the provider’s insurance plan, proof of other coverage will also likely be needed. Read through your policy so you know what to bring when it’s time to collect your car.
Can I rent a car for a month or longer in Mayo Clinic?
Head over to our long-term car rental deals page, enter your trip information and then book your ideal ride. Whether you’re stopping in Mayo Clinic or venturing beyond, Expedia will help you find a long-term rental at an awesome rate.
Where can I find a Mayo Clinic car rental if I am younger than 25?
Some Mayo Clinic outlets will rent cars to drivers under 25, and others won’t. Age policies differ between suppliers, so be prepared to do some research. Also, find out if there are any extra costs. Some businesses will apply a surcharge to young drivers between the ages of 21 and 24. Make sure you read through the terms and conditions to avoid any surprise fees.