Cayo Santa Maria Car Rental

Search and Compare from Car Companies in Cayo Santa Maria

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What happens if I need to cancel my Cayo Santa Maria car reservation?
We appreciate that flexibility on the road is important. That’s why many reservations offer a full refund if canceled a minimum of six hours before picking up the car. It’s still good to go through your rental agreement though because there are some exclusions. If you can’t see any details there, click on our Customer Service Portal.
Why should I rent a Cayo Santa Maria car with Expedia?
From our member exclusive offers and discounts to our terrific package deals, there are so many reasons to book your next car with Expedia. Headed to Cayo Santa Maria? There are car rental companies to take your pick of, with vehicles to suit every style and budget. If you’d like to save more, combine your rental car with your hotel and flights. Ready to take that road trip? We’re ready to get you on your way.
How do I find the best car rental deals on Cayo Santa Maria with Expedia?
Finding the best deal on your Cayo Santa Maria rental car is a cinch with Expedia. Choose your preferred car class, add in a few more details and compare the offers from major suppliers. Why not add flights and hotels to your booking? You’ll score terrific discounts when you create a vacation package.
What do you need to rent a car on Cayo Santa Maria?
You’ll require a valid driver’s license and your credit card to hop behind the wheel on Cayo Santa Maria. You’re likely to also need insurance, whether you’ve got your own or opt for your rental company’s indemnity. Your policy agreement will have details about this.
Can I rent a car for a month or longer on Cayo Santa Maria?
You can. Enjoy taking things a little slower with our fantastic extended rentals. Simply enter your dates and pickup and drop-off locations, and we’ll find you the best long-term car rental deals.
Where can I find a Cayo Santa Maria car rental if I am younger than 25?
You’ll need to look up the age policy of the Cayo Santa Maria rental supplier you’re interested in. Rental companies normally apply a young driver’s surcharge to customers between the ages of 21 and 24, so make sure you understand what extra costs you’re up for. No one likes being hit with unwelcome surprises at the rental desk, so always read over the fine print before finalizing your booking.