Calle 50
Visit Calle 50
Tours & day trips
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City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Private & custom tours
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Jungle quad bike Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
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All-inclusive Sunset Panama Bay Catamaran Tour From Panama City
Classes & workshops
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Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
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Charter Flights Panama City
Popular places to visit

Soho City Center
You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Bingo 90
Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.
National Shrine of the Heart of Mary
You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the casinos in this vibrant area.
Top Calle 50 Hotel Deals

Hotel Riu Plaza Panama

Megapolis Hotel Panamá

Sheraton Grand Panama

JW Marriott Panama

Decapolis Hotel Panama City

Riande Urban Hotel

Hospedium Princess Hotel Panama

Las Americas Golden Tower Panama

The Executive Hotel
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Holidays and getaways similar to Calle 50
- Hotels Near Calle 50
- Hotels near other Attractions
- More Hotel Options in Calle 50
- Las Americas Golden Tower Panama
- The Executive Hotel
- Courtyard by Marriott Panama Multiplaza Mall
- Ramada Plaza By Wyndham Panama Punta Pacífica
- AC Hotel by Marriott Panama City
- Holiday Inn Panama Distrito Financiero by IHG
- Novotel Panama City
- Plaza Paitilla Inn Hotel
- Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
- Waldorf Astoria Panama
- Hyatt Regency Panama City
- W Panama
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.